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Metabolic and Endocrine Disorders

Metabolic medicine involves care of patients with a wide range of long-term conditions. These include disorders of nutrition and obesity, of calcium and bone, inborn errors of metabolism, lipid metabolism, and diabetes mellitus.

Endocrinology is the study of hormones, Endocrine glands secrete hormones; a hormone is a chemical messenger from one cell (or group of cells) to another. For example, the adrenal glands may secrete adrenalin, which has an effect on several different organs.

Hormones influence or control a wide range of physiological activities, such as growth, development, puberty, alertness, sugar regulation, appetite and bone growth. Problems with hormones and the way they work contribute to some of the major diseases of humankind; for example, diabetes, thyroid conditions, pituitary conditions, some sexual problems, some neurological problems, bone problems, and cancer.

There is a team of hospital Consultants working with the Clinical Research Network: North East North Cumbria to make sure that metabolic and endocrine research happens.  They:

  •  Respond to national strategy for metabolism, endocrinology and obesity
  •  Put people first in research and support activities that enhance meaningful patient and public involvement, engagement and participation in the work of the Clinical Research Network
  • Support the research teams, doctors and nurses to deliver metabolic and endocrine trials in the North East and North Cumbria

The Clinical Research Network provides funding for research staff to work alongside metabolic and endocrine doctors and nurses in our local hospitals.  Together they offer patients opportunities to take part in research trials.  Research staff work in the following hospitals and Primary Care Organisations:

  •  City Hospitals Sunderland NHS Foundation Trust
  •  County Durham and Darlington NHS Foundation Trust
  •  Gateshead Health NHS Foundation Trust
  •  NHS Durham Dales, Easington and Sedgefield CCG
  •  NHS Gateshead CCG
  •  NHS Newcastle West CCG
  •  NHS North Tyneside CCG
  •  NHS Northumberland CCG
  •  NHS South Tyneside CCG
  •  NHS Sunderland CCG
  •  North Tees and Hartlepool NHS Foundation Trust
  •  South Tees Hospitals NHS Foundation Trust
  •  The Newcastle Upon Tyne Hospitals NHS Foundation Trust

It’s OK to ask – please ask your doctor, nurse or health professional about research trials in your hospital.

Soon we will have a list of all the studies in our region that you can get involved in. In the meanwhile, if you would like to find out more about current and future metabolic and endocrine studies please visit the UK Clinical Research Network Portfolio database at:

You can also find out more information about metabolic and endocrine disorders from the UK Society of Endocrinology and the following web page provides links to patient groups throughout the United Kingdom:

Meet the Team

Dr Salman Razvi

Specialty Lead for Metabolic and Endocrine and Consultant Endocrinologist & Honorary Senior Clinical Lecturer, Gateshead Health NHS Foundation Trust

Professor Mark Walker

Clinical Research Lead and Professor of Molecular Diabetic Medicine, Newcastle University and Honorary Consultant Physician for The Newcastle upon Tyne Hospitals NHS Foundation Trust.

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