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This major trial on proximal humeral fractures led by Professor Amar Rangan was published on the 10th March. The paper is in the top 5% of papers tracked by Altmetric. The study showed no difference in outcomes between undergoing surgery and wearing a sling for proximal humeral fractures. The paper has generated more interest and enthusiasm than the authors expected, with several clinicians around the world hailing it as a ‘landmark trial’ and ‘practice changing study’. Professor Rangan has been fielding media queries and interviews, from local BBC Tees to the New York Times. There would be considerable cost saving to health economies if the findings of the study were widely adopted.

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Clinical Trials in Musculoskeletal Disorders

Select a trial from the list below to find out more about what it’s all about and how you can get involved in helping others.

North East Early Arthritis Cohort

This study aims to diagnose different types of arthritis more accurately and match treatments to patients in a way that controls everybody’s disease even more effectively

”It’s not pain, it’s discomfort”: An investigation

This study hopes to learn if it is possible to design questionnaires that reflect the patients experience of pain and discomfort more accurately.

STRAP Trial – STRAP – Stratification of Biologic Therapies for RA by Pathobiology

The aim of this study is to investigate whether the most effective choice of biologic medicine for people with RA may be guided by examining the joint tissue (synovial tissue) and, in particular, whether different levels of immune cells (called B cells) within the joint can predict response to treatment.

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